Dr. James Ross Fischer

 

Degrees:

B.S., 1962 - Chemistry - University of Idaho

Teaching Experience:

Present Position:

Advising:

• Advisor for Chemistry Major

Contact Information:

Member American Chemical Society since 1966

Teaching: (annual) General Chemistry II, Health Sciences Chemistry, (alternate years) Quantitative Analysis, Instrumental Analysis, Organic Chemistry, Biochemistry, Physics and Astronomy.

Research:

Cobalt complexes as models of vitamin B6, Methylthiomethylphenols and Analytical methods.

Publications:

Richmond, C.G., C.A. Brewster, R.J. Fischer and J.R. Fischer, "Swern Reagent Preparation of Substituted 2-[(methylthio)methyl]phenols", in preparation

Fischer, J.R. and E.H. Abbott, "Vitamin B-6 Model Reactions Part VI - A Hammett Relationship for the Magnitude of Pseudoallylic Proton-Proton Spin Coupling Constants in Substituted Azomethines", Magnetic Resonance in Chemistry, 33, 283-285 (1995)

Bose, K.S., J.R. Fischer and E.H. Abbott, "Vitamin B-6 Model Reactions (V): Synthesis, Conformation and Differential Reactivity of the L-(S,S) and D-(S,S) Diastereoisomers of Bis(pyridoxylidene-L-valinato)cobalt(III) Complexes", J. Coord. Chem., 23, 213-220 (1991).

Sykes, A., R. Larsen, J. Fischer and E. Abbott, "Vitamin B6 Model Reactions (IV): Carbon-Hydrogen Bond Breaking Reactions and the Crystal and Molecular Structure of the Bis(pyridoxylideneglycinato)cobaltate (III) Anion", Inorganic Chemistry, 30, 2913-2916 (1991).

Fischer, J.R., R.J. Fischer and E.H. Abbott, "Models of Vitamin B-6 (III): Steric and Electronic Effects in Carbon-Hydrogen Bond Breaking Reactions of Bis(salicylideneglycinato)cobaltate(III) Anions", Inorganic Chemistry, 29, 1682-1687 (1990).

Sykes, A., R. Larsen, J. Fischer and E. Abbott, "Preferential Catalysis of Model Reactions in the Cobalt(III) Complex of the Vitamin B-6 Schiff Base of Glycine", Rev. Port. Quim. 27, 308 (1985).

MacLeod, W. and J. Fischer, "Intercalibration of Analytical Laboratories" in Proceedings of a Symposium on Preliminary Results from the September 1979 Researcher/Pierce Ixtoc-I Cruise, (1980), National Oceanic and Atmospheric Administration Publications Office, Boulder, CO.

Fischer, J. and E. Abbott, "Differential Exchange of a-Methylene Protons of Bis(pyridoxylideneglycin- ato)cobalt(III); Inferences for Vitamin B6 Catalyzed Reactions", J. Am. Chem. Soc. 101, 2781 (1979).

Fischer, J. and J. Hurst, "Internal Electron Transfer in Xanthine Oxidase", Bioinorganic Chemistry 9, 181 (1978).

McCormick, J., J. Fischer, and J. Pachlatko, "Formation of Hydrogen Peroxide from the Photooxidation of Tryptophan and Related Substances", in Symposium on Biological Effects and Measurement of Light Sources, D.G. Hazzard (ed.), Rockville, MA (1976) (HEW Health, Rockville, MA).

McCormick, J., J. Fischer, J. Pachlatko and A. Eisenstark, "Characterization of a Cell-Lethal Product from the Photooxidation of Tryptophan: Hydrogen Peroxide", Science 191, 468 (1976).

McCormick, J., J. Fischer and T. Schafer, "Chromatographic Purification and Characterization of Hydrogen Peroxide", J. Chrom. 117, 428 (1976).

Fischer, J. Studies of the Action of Molecular Singlet Oxygen on Proteins and Amino Acids, Doctoral Thesis, Montana State University (1974).

Fischer, J., G. Julian, and S. Rogers, "Oxidation of Amino Acids By Singlet Oxygen: I. Comparison of Dye Sensitized Photooxidation and Microwave Generated Singlet Oxidation", Physiol. Chem. and Physics 6, 179 (1974).

Cooley, J., P. Jacobs, J. Fischer and S. Jeppeson, "Preparation of 1-Benzyloxy-3-arylureas, 1-Benzyloxy-3-alkylureas and 1,5-Diphenyl-3-benzyloxybiuret", J. Chem. and Eng. Data 19, 100 (1974).

Fischer, J., Some Reactions of N-Acyl-O-alkylhydroxylamine Compounds, Master¹s Thesis, University of Idaho, (1967).

Papers Presented At Meetings: (presented by underlined author)

J. Fischer "Small College us of the Anasazi Instruments FT-NMR Upgrade of an Older Permanent Magnet CW-NMR", Joint Northwest and Rocky Mountain Regional meeting, Idaho Falls, ID 2000.

J. Fischer , J. Fitzgerald, J Loftis and D. Utz, "Toward Moffatt-Pfitzner Preparations of Pyridoxal Analogs II", Joint Southwest and Rocky Mountain Regional meeting, El Paso TX, 1999.

B. Bruessel, D. Utz and J. Fischer "Swern-Moffatt-Pfitzner Preparation of Pyridoxal Analogs", Rocky Mountain Regional American Chemical Society, Tucson, AZ, 1998.

J. Fischer and E. Abbott, "A Hammett Relationship for the Magnitude of Pseudoallylic Proton-Proton Spin Coupling Constants in Substituted Azomethines", New Mexico Regional Nuclear Magnetic Resonance meeting, Silver City, NM.

L. Fischer and J. Fischer, "Analysis of Soluble Iron(II) in Mine Blasting Holes", Rocky Mountain Regional American Chemical Society, Albuquerque, NM, 1992.

J. Fischer, A. Bell, L. Fischer, R. Fischer, F. Richmond, B. Roberts, B. Thomas and E. Abbott, "Swern-Moffatt Preparation of ortho-Methylthiomethylphenols", Northwest Regional American Chemical Society, LeGrande, OR, 1991.

J. Fischer and E. Abbott, "Acid Range Catalysis of Glycyl Hydrogen Exchange in Sodium Bis(pyridoxyl-ideneglycinato)cobaltate(III)", Joint Northwest-Rocky Mountain Regional American Chemical Society, Salt Lake City, UT, 1990.

J. Fischer, M. Kappel, A. Sykes and E. Abbott, "Vitamin B6 Models: Stereospecificity and Reaction Rate Factors in Pyridoxal- and Substituted Salicylaldehyde-Glycine-Cobalt(III) Models", Northwest Regional American Chemical Society, Bellingham, WA, 1987.

J. Fischer, "Kinetic Study of B6 Models", 8th New Mexico Regional Nuclear Magnetic Resonance meeting, Silver City, NM, 1985.

J. Fischer, M. Kappel, D. Lambert, J. Lopez, G. Stanford, W. van Dran and P. Welsh, "Substituted Salicylaldehyde-Glycine-Cobalt(III) Compounds for Models of Vitamin B6", Rocky Mountain Regional Chemical Society, Albuquerque, NM, 1984.

J. Fischer and E. Abbott, "Racemization and Alpha-Hydrogen Exchange in the Amino Acids of Bis(pyridoxylideneaminoacido)cobalt(III) Complexes", Northwest Regional American Chemical Society, Seattle, WA, 1978.

J. Fischer and S. Rogers, "Hematoporphyrin-Sensitized Photooxidation of Proteins", Northwest Regional American Chemical Society, Portland, OR, 1977.

J. Fischer, L. Hulett and J. Hurst, "Transient-Kinetic Investigations of Biological Reactions", Northwest Regional American Chemical Society, Portland, OR, 1977.

J. Fischer and J. McCormick, "Toward Purification and Characterization of a Tryptophan-Near Ultraviolet Photoproduct Toxic to Recombinationless Bacteria", Missouri Branch, American Society for Microbiology, Columbia, MO, 1975.

J. Fischer and S. Rogers, "Anomalous Behavior of Singlet Oxygen Mediated Oxidations", Northwest Regional American Chemical Society, Cheney, WA, 1974.

J. Fischer, G. Julian and S. Rogers, "Effects of Microwave Generated Singlet Oxygen on Amino Acids", Northwest Regional American Chemical Society, Pullman, WA, 1973.

R. Fischer, G. Stanford, E. Abbott and J. Fischer, "Vitamin B6 Models: Kinetics of Hydrogen-Deuterium Exchange in Three Isomeric Methoxysalicylaldehyde-Glycine-Cobalt(III) Complexes", Northwest Regional American Chemical Society, Bellingham, WA, 1987.

E. Abbott, A. Sykes, R. Larsen and J. Fischer, "The Influence of Structure on the Preferential Catalysis of Vitamin B6 Model Reactions", 189th American Chemical Society National, Miami Beach FL, 1985.

J. McCormick, J. Fischer, J. Pachlatko and A. Eisenstark, "Characterization of a Cell-Lethal Product from the Unsensitized Photooxidation of Tryptophan: Hydrogen Peroxide", Midwest Regional American Chemical Society, Carbondale, IL, 1975.

A. Eisenstark, J. McCormick, F. Landa, J. Fischer and B. Landa, "Characterization of Near-UV Photoproducts of Tryptophan That Are Lethal to Bacteria" , American Society of Microbiology, New York, NY, 1975.

Instrumentation at WNMU Chemistry

In Use in Connection with Classes or Current Research:

PE Lambda 4B ultraviolet-visible spectrophotometer

IL 451 atomic absorption spectrophotometers

MIDAC M Series Fourier transform infrared spectrophotometer

Varian 3700 gas chromatograph

Altech 112 high performance liquid chromatograph

PE 203 spectrofluorimeter

Varian EM360A nuclear magnetic resonance spectrometer fitted with an Anazazi EFT FT-NMR modification

Nucleus 500 nuclear scaler

Fisher 750 specific ion analyzer

Spectronic 20 visible spectrophotometers